Seasonal flu vaccine: In rare cases, some patients who received the flu vaccine experienced mild eye symptoms like eye redness, eye pain and blurred vision. It’s worth noting that there are multiple common vaccines that are known to be associated with side effects of the eyes: This link is possible but not yet established and still being explored. There have been claims recently that the MHRA’s Yellow Card Scheme report indicates that mRNA vaccines cause blindness and other eye disorders. Corneal nerve damage has been associated with “long COVID” and stroke as a result of COVID-19. One study showed nearly one in four children treated for COVID-19 at a Chinese hospital in early 2020 had mild eye problems, including eye discharge, conjunctivitis (pink eye), eye rubbing, eye pain, and eyelid swelling. Regardless of whether the connection is causal or not, current data suggests that the incidence rate of ocular symptoms is considerably lower in vaccinated subjects than in COVID-19 patients, particularly among children. In the meantime, physicians should be aware of the possible associations between COVID-19 vaccines and eye symptoms for the early diagnosis and treatment of potential vision problems or other complications. This is why research is ongoing to understand the connection. It’s possible that certain demographics were not represented in their studies, for instance, or that the sample sizes were not large enough to catch this side effect. However, this does not mean it’s not possible that mRNA vaccines might cause eye problems in very rare cases for a number of reasons. In the original Phase 3 trials of both the Pfizer-BioNTech vaccine and the Moderna vaccines–which were large controlled, randomized studies–eye problems were not reported as a side effect. The best way to understand a connection between a vaccine and an outcome is through a large scientific trial, and the only true way to definitively know if a vaccine causes an outcome is through a large, controlled, randomized trial (where there is a vaccine group and control group). The same is true of case reports in science. and the U.K.’s MHRA Yellow Card Scheme–are good ways of identifying a potential side effect if high numbers of an event are routinely reported, but are not good ways of establishing a definitive link. To be sure, country level reporting systems–such as the Vaccine Adverse Event Reporting System (VAERS) in the U.S. The UK's Medicines and Healthcare products Regulatory Agency (MHRA) reporting system known as the Yellow Card Scheme has had 132 self-reported cases of blindness and 6,682 overall eye disorders reported since vaccine rollouts began across about 51 million people. The ocular manifestations occurred up to forty-two days after vaccination, and vaccine-induced immunologic responses could be responsible. One systematic review of multiple studies, case reports, and letters found that "ocular manifestations" (an eye condition that directly or indirectly results from a disease process in another part of the body) after receiving COVID-19 vaccines may appear on the eyelid, cornea and ocular surface, retina, uvea, nerve, and vessel. What we know so far about the potential connection between mRNA COVID-19 vaccines and side effects of the eyes comes mostly from country-level reporting systems and case reports. There have not been enough cases documented in reporting systems or studies to determine whether these side effects are due to the vaccines or due to coincidence. However, there are a number of case reports of blindness and other ocular side effects (eye problems) that are being researched to better understand if there is a causal link or not. However, there are a number of case reports of blindness and other ocular side effects (eye problems) that have raised concerns among side effects and that are being researched to better understand if there is a causal link or not it’s possible that there is but there have not been enough reports in reporting systems or studies to determine whether these side effects are due to the vaccines or due to coincidence.Ĭurrently, there is no established link connecting mRNA COVID-19 vaccines to blindness or other eye problems. Currently, there is no established causal link that connects mRNA COVID-19 vaccines to blindness or other eye problems.
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